Microcusteio do sequenciamento do exoma e de Sanger na cardiomiopatia hipertrófica no Sistema Único de Saúde
DOI:
https://doi.org/10.21115/JBES.v18.p97-107Palavras-chave:
Custos de cuidados de saúde, Testes Genéticos, cardiomiopatia hipertrófica, Sequenciamento do ExomaResumo
Objetivo: Estimar os custos diretos do sequenciamento do exoma no paciente com cardiomiopatia hipertrófica e do sequenciamento de Sanger em seus familiares de primeiro grau, na perspectiva do Sistema Único de Saúde (SUS), utilizando a metodologia de microcusteio. Métodos: Foi realizada uma análise de microcusteio com o objetivo de identificar, quantificar e valorar os recursos necessários para cada exame, incluindo insumos, depreciação e manutenção de equipamentos, transporte, recursos humanos e custos administrativos. O estudo foi conduzido em um hospital federal, onde está localizada uma rede especializada em genômica cardiovascular. Além disso, foram realizadas análises de sensibilidade determinística e probabilística para avaliar a robustez das estimativas. Resultados: O custo do sequenciamento do exoma foi de R$ 1.547,10 por paciente, e o custo do sequenciamento de Sanger foi de R$ 414,75 por familiar. Os insumos representaram 80% do custo total em ambos os exames. As análises de sensibilidade confirmaram a robustez das estimativas. Conclusão: Este estudo apresenta a primeira estimativa detalhada de microcusteio do sequenciamento do exoma e de Sanger para cardiomiopatia hipertrófica no Brasil. Os custos estimados podem subsidiar a definição de valores de reembolso e orientar políticas públicas para a incorporação desses exames no SUS. Estratégias como a centralização em unidades de referência são fundamentais para viabilizar sua implementação e ampliar o acesso ao diagnóstico genético na rede pública.
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